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Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral

Haiyan LU, Yongting WANG, Falei YUAN, Jianrong LIU, Lili ZENG, Guo-Yuan YANG

Frontiers of Medicine 2011, Volume 5, Issue 1,   Pages 86-93 doi: 10.1007/s11684-011-0118-x

Abstract: NT-1 was shown to be able to stimulate the proliferation and migration of human cerebral endothelialusing an adeno-associated virus (AAV) vector (AAV-NT-1) into mouse brain followed by transient middle cerebral

Keywords： adeno-associated virus     angiogenesis     gene transfer     ischemia     middle cerebral artery occlusion     netrin-1    

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Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 2,   Pages 197-205 doi: 10.15302/J-FASE-2018245

Abstract: activity of rats in an open-field test, which was associated with attenuated neuronal damage induced by ischemiaserum SOD activity was significantly greater, MDA level lower in the leonurine group as compared with ischemiaIn addition, GABA content in the cerebral cortex was significantly greater in high-dose leonurine groupTaken together, our results demonstrated that leonurine attenuated brain injury during ischemia via antioxidative

Keywords： cerebral ischemia     GABA     neuroprotection     leonurine     SOD    

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survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats with cerebralischemia

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Frontiers of Medicine 2021, Volume 15, Issue 3,   Pages 472-485 doi: 10.1007/s11684-021-0832-y

Abstract: conditioning could increase the survival of transplanted neuronal progenitor cells (NPCs) in rats with cerebralischemia but could also hinder neuronal differentiation partly by suppressing mitochondrial metabolism

Keywords： neuronal progenitor cells     resveratrol     cerebral ischemia     neuronal differentiation     mitochondrial metabolism    

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Fastigial Nucleus Electrical Stimulation and Central Neurogenic Neuroprotection

Dong Weiwei

Strategic Study of CAE 2001, Volume 3, Issue 11,   Pages 32-38

Abstract:

Brian can protect itself from ischemia and/or hypoxia by two distinct mechanisms which probably involvemode of neuroprotection is not restricted to focal ischmia,it also protects the brain against global ischemiaexpression of many detrimental factors including Caspase-3 and NF-kappaB, and reduced immunoreactivity of cerebral

Keywords： neuroprotection     conditioned     fastigial neucleus     stimulation     cerebral ischemia    

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Stroke prevention: an update

Marie-Germaine Bousser

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 22-34 doi: 10.1007/s11684-012-0178-6

Abstract: treatments addressing the specific subtypes of stroke, such as antiplatelet drugs for the prevention of cerebral

Keywords： stroke     prevention     vascular risk factors     cerebral infarction     cerebral hemorrhage     anti-thrombotic drugs    

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The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 329-331 doi: 10.1007/s11684-012-0211-9

Abstract: ow in the early phase of reperfusion, which has been found to be protective against renal ischemia-reperfusionthe allograft renal vein was twisted because of the surgeon’s mistake, which caused the warm ischemiaallograft restored blood flow without second reperfusion and cold preservation after 9 min of warm ischemia

Keywords： renal transplantation     vein twist     ischemia-reperfusion injury    

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Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 317-322 doi: 10.1007/s11684-010-0035-4

Abstract: The inhibitory effect of different reperfusion periods 45 min following hepatic ischemia on the expressionrandomly divided into four groups: normal control group (CO group), sham-operated group (SO group), ischemiaIt is suggested that the digestive tract congestion injury caused by liver ischemia can upregulate the

Keywords： hepatic ischemia-reperfusion     digestive tract congestion     cholecystokinin     vasoactive intestinal peptide    

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Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Frontiers of Medicine 2015, Volume 9, Issue 3,   Pages 368-373 doi: 10.1007/s11684-015-0403-1

Abstract: Glucagon-like peptide-2 (GLP-2) has potent anti-inflammatory effects and protects against experimental ischemiaThe first group was the control group; the second group was the vehicle-treated hepatic ischemia/reperfusionA portal triad was created to induce ischemia with a vascular atraumatic clamp.

Keywords： ischemia/reperfusion     liver     glucagon-like peptide-2     alanine aminotransferase    

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Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 433-437 doi: 10.1007/s11684-007-0085-4

Abstract: The effect of peripherally administered oxytocin (OT) on gastric ischemia-reperfusion injury (GI-RI)The animal GI-RI model was established by clamping the celiac artery for 30 min to induce ischemia andresults indicated that the oxytocin could significantly protect gastric mucosal against injury induced by ischemia-reperfusion

Keywords： control     significant difference     surgical     statistical significance     Sprague-Dawley    

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Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 87-92 doi: 10.1007/s11684-007-0017-3

Abstract: The aim of this paper is to explore the effect of intestinal ischemia/reperfusion (I/R) injury on leptinintestinal I/R injury model of rats was made; the rats were grouped according to the time of after 60 min ischemiaCompared with the levels before the injury, serum leptin in 60 min ischemia/30 min reperfusion (I60´R30

Keywords： significant difference     intestinal I/R     transcriptase-polymerase     metabolic     central secretory    

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Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Engineering doi: 10.1016/j.eng.2023.06.009

Abstract: Myocardial ischemia is a serious threat to human health, and vascular dysfunction is its main cause.Buxu Tongyu Granule (BXTY) is an effective traditional Chinese medicine (TCM) for treating myocardial ischemiaIn this study, we demonstrate that BXTY ameliorates myocardial ischemia by activating the soluble guanylateThe results showed that BXTY alleviated the symptoms of myocardial ischemia induced by pituitrin in miceIn conclusion, BXTY can improve the symptoms of acute myocardial ischemia in mice, and activating the

Keywords： Myocardial ischemia     Vasomotion     Soluble guanylate cyclase     Buxu Tongyu Granule    

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Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Frontiers of Medicine doi: 10.1007/s11684-023-1041-7

Abstract: vaccines on stroke, including arterial stroke (ischemic stroke and hemorrhagic stroke) and venous stroke (cerebral

Keywords： SARS-CoV-2     ischemic stroke     stroke     hemorrhagic stroke     cerebral venous thrombosis     vaccination    

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Implications of astrocytes in neurovascular coupling

You ZHOU MD, Chang-Kai SUN MD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 43-45 doi: 10.1007/s11684-010-0019-4

Abstract: The close spatial and temporal relationship between neural activity and cerebral blood flow (CBF) isaction of multiple mediators that originate from different cells and act at different levels of the cerebral

Keywords： cerebral blood flow     neurovascular coupling     astrocyte    

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Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Frontiers of Medicine 2018, Volume 12, Issue 2,   Pages 123-129 doi: 10.1007/s11684-017-0563-2

Abstract: barrier destruction is widely observed among patients receiving liver transplant and suffering from ischemia

Keywords： gut microbial balance     liver transplantation     ischemia–reperfusion     acute rejection    

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The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 391-395 doi: 10.1007/s11684-008-0075-1

Abstract: brains of Kunming mice, six-month-old mice ( = 72) were pretreated with heat stress and subsequent ischemiarandomly divided into four groups: (1) normal control group; (2) heat stress pretreatment followed by ischemiaand reperfusion group (HS/IR); (3) ischemia and reperfusion group (IR); (4) heat stress group (HS).

Keywords： calcitonin gene-related     subsequent ischemia/reperfusion     computer     cerebrum     CGRP excretion    

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Title Author Date Type Operation

Overexpression of netrin-1 improves neurological outcomes in mice following transient middle cerebral

Haiyan LU, Yongting WANG, Falei YUAN, Jianrong LIU, Lili ZENG, Guo-Yuan YANG

Journal Article

Leonurine protects ischemia-induced brain injury via modulating SOD, MDA and GABA levels

Shilei ZHENG, Jingru ZHU, Jiao LI, Shuang ZHANG, Yunfei MA

Journal Article

survival and neuronal differentiation of hypoxia-conditioned neuronal progenitor cells in rats with cerebralischemia

Yao Yao, Rui Zhou, Rui Bai, Jing Wang, Mengjiao Tu, Jingjing Shi, Xiao He, Jinyun Zhou, Liu Feng, Yuanxue Gao, Fahuan Song, Feng Lan, Xingguo Liu, Mei Tian, Hong Zhang

Journal Article

Fastigial Nucleus Electrical Stimulation and Central Neurogenic Neuroprotection

Dong Weiwei

Journal Article

Stroke prevention: an update

Marie-Germaine Bousser

Journal Article

The second short-term warm ischemia after vascular anastomosis did not affect early renal function recovery

Tao Qiu, Jiangqiao Zhou, Xiuheng Liu, Minghuan Ge, Zhiyuan Chen

Journal Article

Effect of salvia miltiorrhiza pretreatment on the CCK and VIP expression in hepatic ischemia-reperfusion-induced

Zhi-Yong ZHANG, Xiao-Ping CHEN, Qi-Ping LU

Journal Article

Glucagon-like peptide-2 exhibits protective effect on hepatic ischemia-reperfusion injury in rats

Naci Topaloğlu,Adem Küçük,Şule Yıldırım,Mustafa Tekin,Havva Erdem,Mustafa Deniz

Journal Article

Effect of oxytocin on gastric ischemia-reperfusion injury in rats

ZHANG Wenwen, ZHANG Jianfu, ZHANG Yongmei, XU Ming

Journal Article

Effect of intestinal ischemia/reperfusion injury on leptin and orexin-A levels

LIN Ji, YAN Guangtao, HAO Xiuhua, ZHANG Kai, GAO Xiaoning, LIAO Jie

Journal Article

Buxu Tongyu Granule Alleviates Myocardial Ischemia by Activating Vascular Smooth Muscle Cell Soluble

Shuang Yang,Yixiu Zhao,Xiaoling Cheng,Tingting Zhan,Jiaying Tian,Xue Liu,Chunyue Ma,Zhiqi Wang,Luying Jin,Qian Liu,Yanli Wang,Jian Huang,Jinhui Wang,Yan Zhang,Baofeng Yang,

Journal Article

Epidemiology, pathogenesis, and management of coronavirus disease 2019-associated stroke

Journal Article

Implications of astrocytes in neurovascular coupling

You ZHOU MD, Chang-Kai SUN MD,

Journal Article

Gut microbial balance and liver transplantation: alteration, management, and prediction

Xinyao Tian, Zhe Yang, Fangzhou Luo, Shusen Zheng

Journal Article

The early signal substances induced by heat stress in brains of mice

WANG Chunxu, WANG Hanxing

Journal Article